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POLYMYXIN B SULFATE, BACILLUS POLYMYXA

polymyxin B standard solution

CAS: 1405-20-5

Molecular Formula: C56H100N16O17S

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POLYMYXIN B SULFATE, BACILLUS POLYMYXA - Names and Identifiers

Name polymyxin B standard solution
Synonyms POLYMYXIN B
Polymyxin B (PMB)
POLYMYXIN B (PMB)
Polymyxin B sulfate
POLYMYXIN B SULFATE
POLYMIXIN B SULFATE
Polymyxin B Sulphate
Polymyxin B solution
POLYMYXIN B SULPHATE
POLYMYXIN-B 2,5-SULFATE
Polymyxin B 2,5-SULFATE
polymyxin B sulfate usp
Polymyxin B sulfate salt
POLYMYXIN B SULFATE SALT
polymyxin B standard solution
POLYMYXIN B SULFATE, BACILLUS POLYMYXA
N~2~-[4-amino-2-(formylamino)butanoyl]-N-(3-amino-1-{[6,9,18-tris(2-aminoethyl)-15-benzyl-3-(2-hydroxyethyl)-12-(2-methylpropyl)-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptaazacyclotricosan-21-yl]carbamoyl}propyl)homoserinamide sulfate (salt)
N-[3-amino-1-[[1-[[3-amino-1-[[6,9,18-tris(2-aminoethyl)-15-benzyl-3-(1-hydroxyethyl)-12-isobutyl-2,5,8,11,14,17,20-heptaoxo-1,4,7,10,13,16,19-heptazacyclotricos-21-yl]carbamoyl]propyl]carbamoyl]-2-hydroxy-propyl]carbamoyl]propyl]-6-methyl-octanamide,sulfuric acid
CAS 1405-20-5
EINECS 215-774-7
InChI InChI=1/C48H82N16O13.H2O4S/c1-27(2)24-37-47(76)59-32(11-19-52)41(70)56-31(10-18-51)43(72)61-35(14-22-65)39(68)54-21-13-34(45(74)57-33(12-20-53)44(73)64-38(48(77)63-37)25-28-6-4-3-5-7-28)60-42(71)30(9-17-50)58-46(75)36(15-23-66)62-40(69)29(8-16-49)55-26-67;1-5(2,3)4/h3-7,26-27,29-38,65-66H,8-25,49-53H2,1-2H3,(H,54,68)(H,55,67)(H,56,70)(H,57,74)(H,58,75)(H,59,76)(H,60,71)(H,61,72)(H,62,69)(H,63,77)(H,64,73);(H2,1,2,3,4)

POLYMYXIN B SULFATE, BACILLUS POLYMYXA - Physico-chemical Properties

Molecular FormulaC56H100N16O17S
Molar Mass1301.56
Melting Point217-220°C (dec.)
Boling Point1611°C at 760 mmHg
Flash Point928.1°C
Water SolubilitySoluble in water at 50mg/ml/n
Solubility Dissolve 100 mg/mL in water, almost insoluble in ethanol and DMSO
Vapor Presure0mmHg at 25°C
AppearanceWhite to light yellow powder
Colorcolorless or slightly yellow
Merck14,7573
pKapKa 8.9 (Uncertain)
PHpH (10g/L, 25℃) : 4.5～7.0
Storage Condition2-8°C
StabilityHygroscopic
SensitiveSensitive to light
MDLMFCD00131991
UseThis product is for scientific research only and shall not be used for other purposes.

POLYMYXIN B SULFATE, BACILLUS POLYMYXA - Risk and Safety

Hazard SymbolsXn - Harmful
Harmful
Risk Codes22 - Harmful if swallowed
Safety DescriptionS22 - Do not breathe dust.
S24/25 - Avoid contact with skin and eyes.
UN IDs3249
WGK Germany3
RTECSTR1150000
FLUKA BRAND F CODES3-8-10
HS Code2941 90 00
Hazard Class6.1(b)
Packing GroupIII

POLYMYXIN B SULFATE, BACILLUS POLYMYXA - Reference

Reference
Show more
1. Zhou Qing. Analysis of Lipid A Structure of Vibrio parahaemolyticus and Study on Related Genes [D]. Jiangnan university, 2020.
2. [IF = 10.588] Fangchao Yin et al."A portable digital optical kanamycin sensor developed by surface-anchored liquid crystal droplets." J Hazard Mater. 2021 Oct;420:126601
3. [IF = 7.086] Juan Liu et al."Differential regulation and the underlying mechanisms of clay minerals to Escherichia coli under the stress of polymyxin B: Comparing halloysite with kaolinite." Chemosphere. 2021 Feb;265:129095
4. [IF = 6.953] QingChi Wang et al."Structural characteristics and immune-enhancing activity of an extracellular polysaccharide produced by marine Halomonas sp. 2E1." Int J Biol Macromol. 2021 Jul;183:1660
5. [IF = 2.281] Zhiqiang Zhang et al."Contribution of the colicin receptor CirA to biofilm formation, antibotic resistance, and pathogenicity of Salmonella Enteritidis." J Basic Microb. 2020 Jan;60(1):72-81

POLYMYXIN B SULFATE, BACILLUS POLYMYXA - Introduction

Polymyxin is a group of polypeptide antibiotics produced by Bacillus polymyxa (bacilluspolymyxa). Polymyxin B and E are used for medicinal purposes, and their sulfates are commonly used. The antibacterial spectrum and clinical application of polymyxin B sulfate are similar to those of polymyxin E. It has inhibitory or bactericidal effects on gram-negative bacilli, such as Escherichia coli, Pseudomonas aeruginosa, paracilli, Klebsiella pneumoniae, acidophilus, pertussis and Shigella.
Last Update：2022-10-16 17:13:51
POLYMYXIN B SULFATE, BACILLUS POLYMYXA
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Shanghai Yuanye Bio-Technology Co., Ltd.
Featured ProductsSpot supply
Product Name: Polymyxin B sulfate Visit Supplier Webpage Request for quotation
CAS: 1405-20-5
Tel: 18301782025
Email: 3008007409@qq.com
Mobile: 18021002903
QQ: 3008007409 Click to send a QQ message
Wechat: 18301782025
Hubei YoungXin Pharmaceutical Tech Co.,Ltd.
Spot supply
Product Name: Polymyxin B Sulfate Visit Supplier Webpage Request for quotation
CAS: 1405-20-5
Tel: 0714-3999186
Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052 Click to send a QQ message
Wechat: 15671228036
Guangzhou Yuanda New Material Co.,Ltd
Product Name: Polymyxin B sulfate Request for quotation
CAS: 1405-20-5
Tel: +86 19849939632
Email: 2470479589@qq.com
Mobile: +86 19849939632
QQ: 2470479589 Click to send a QQ message
Wechat: +86 19849939632
Hefei TNJ Chemical Industry Co.,Ltd.
Product Name: polymyxin B standard solution Request for quotation
CAS: 1405-20-5
Tel: 0086-551-65418684
Email: sales@tnjchem.com
　　　　 info@tnjchem.com
Mobile: 0086 189 4982 3763
QQ: 2881500840 Click to send a QQ message
Wechat: 0086 189 4982 3763
WhatsApp: 0086 189 4982 3763
Product List: View Catalog
Jiangxi Volivo biotechnology CO.,LTD
Product Name: Polymyxin B sulfate Request for quotation
CAS: 1405-20-5
Tel: 0797-6906737
Email: alina-lee@volivo.cn
Mobile: 13330160192
QQ: 1961688258 Click to send a QQ messageSend QQ message
Shenzhen Shengda Pharma Limited
Product Name: Polymyxin B sulfate Request for quotation
CAS: 1405-20-5
Tel: 0755-85269922
Email: sales@shengdapharm.com
Mobile: 13424394241
QQ: 1799060443 Click to send a QQ messageSend QQ message
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POLYMYXIN B SULFATE, BACILLUS POLYMYXA
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